This is not a comprehensive list, simply some articles I have found along the way.
“Results showed that acute exposure to Roundup(®) (30min) increases (45)Ca(2+) influx by activating NMDA receptors and voltage-dependent Ca(2+) channels, leading to oxidative stress and neural cell death. The mechanisms underlying Roundup(®)-induced neurotoxicity also involve the activation of CaMKII and ERK. Moreover, acute exposure to Roundup(®) increased (3)H-glutamate released into the synaptic cleft, decreased GSH content and increased the lipoperoxidation, characterizing excitotoxicity and oxidative damage. We also observed that both acute and chronic exposure to Roundup(®) decreased (3)H-glutamate uptake and metabolism, while induced (45)Ca(2+) uptake and (14)C-MeAIB accumulation in immature rat hippocampus. Taken together, these results demonstrated that Roundup(®) might lead to excessive extracellular glutamate levels and consequently to glutamate excitotoxicity and oxidative stress in rat hippocampus.”
“As I said, the glutamate is very interesting because glyphosate disrupts the body’s ability to metabolize glutamate, so the glutamate becomes toxic and gets into the brain.”
“Manganese (Mn) is an often overlooked but important nutrient, required in small amounts for multiple essential functions in the body. A recent study on cows fed genetically modified Roundup®-Ready feed revealed a severe depletion of serum Mn. Glyphosate, the active ingredient in Roundup®, has also been shown to severely deplete Mn levels in plants. Here, we investigate the impact of Mn on physiology, and its association with gut dysbiosis as well as neuropathologies such as autism, Alzheimer’s disease (AD), depression, anxiety syndrome, Parkinson’s disease (PD), and prion diseases. Glutamate overexpression in the brain in association with autism, AD, and other neurological diseases can be explained by Mn deficiency.”
While there has been a lot of information on the role of glyphosate (found in RoundUp) and glutamate/autism/gut health/etc but maybe we should be directing our attention to the herbicide, Glufosinate? Glufosinate is growing in popularity and works similarly to glyphosate but is the glutamate analog instead of glycine. My guess is it will work similarly to glyphosate, but will mimic glutamate instead. “Glufosinate is a structural analog of glutamate and inhibits the glutamine synthetase. The result is a rapid build-up of a high ammonia level and a concomitant depletion of glutamine and several other amino acids in the plant.” https://www.ncbi.nlm.nih.gov/pubmed/7938785
Stephanie Seneff mentions it in this clip around the 56 min mark…https://www.betterhealthguy.com/episode39