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Lowering Glutamate | Valerian Root

Valerian Root – Increases GABA. “ In addition, pretreatment with valerian extract or valerenic acid decreased the brainstem inhibitory effects produced by muscimol (both P < 0.05), suggesting that these compounds play an important role in the regulation of GABAergic activity. Data from this study suggest that the pharmacological effects of valerian extract and valerenic acid are mediated through modulation of GABA(A) receptor function” https://www.ncbi.nlm.nih.gov/pubmed/14742369 Why Is This Important? Glutamate is also the most abundant neurotransmitter, responsible for regulating over 50% of the nervous system. It is classified as an excitatory neurotransmitter, which means it excites [...]

Lowering Glutamate | Valerian Root2021-09-16T12:59:58-04:00

Lowering Glutamate | Lemon Balm

Lemon Balm (Melissa officinalis L)- increases GABA which helps lower glutamate and establish balance between the two neurotransmitters. “These results suggest that MOE increases cell proliferation, neuroblast differentiation and integration into granule cells by decreasing serum corticosterone levels as well as by increasing GABA levels in the mouse DG.” https://www.ncbi.nlm.nih.gov/pubmed/21076869 Why Is This Important? Glutamate is also the most abundant neurotransmitter, responsible for regulating over 50% of the nervous system. It is classified as an excitatory neurotransmitter, which means it excites or stimulates nerve cells located throughout the nervous system. Glutamate also has [...]

Lowering Glutamate | Lemon Balm2021-09-16T13:32:04-04:00

Lowering Glutamate | Acorus Gramineus (Calamus Root aka Sweet Flag)

Acorus Gramineus (Calamus Root aka Sweet Flag) essential oil has shown to inhibit NMDA (glutamate) receptor activity, increase GABA and lower glutamate upon inhalation. We have been able to source this, here.  I will occasionally add this to our diffuser to help calm any crazy days. “These results demonstrated that EO extracted from AGR exhibited neuroprotective effects on cultured cortical neurons through the blockade of NMDA receptor activity, and that the glycine binding site appeared not to be the major site of action. ” http://www.sciencedirect.com/science/article/pii/S0024320501009444   “Furthermore, inhalation impressively inhibited the activity of gamma-aminobutyric acid (GABA) transaminase, [...]

Lowering Glutamate | Acorus Gramineus (Calamus Root aka Sweet Flag)2021-09-22T12:03:06-04:00
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