Lowering Glutamate | B3

Vitamin B3 (Niacin, Nicotinic Acid)- Found high in liver, anchovies, tuna, chicken breast I would not encourage the use of this supplement unless you are well aware of your methylation status. “Nicotinic acid requires SAMe to be metabolized. SAMe is a major methyl donor. Thus, when one consumes niacin, SAMe gets used up and methyl donors drop. Thereby excessive methylation goes away. Nicotinic acid also supports the elimination of glutamate. Many with elevated levels of glutamate do not do well with methylfolate or any type of folate until the levels of glutamate are balanced.” [...]