Lowering Glutamate | Magnesium

Magnesium- In our experience, magnesium has made the biggest impact in reducing our symptoms within a flare. Magnesium protects against glutamate damage, sits on the NMDA glutamate receptor, calms cells, helps to raise GABA, improves motility, and can help to resolve many various health issues. It is also my understanding that one will quickly burn through magnesium due to neuron firing when in an excitotoxic state (or a flare). Low magnesium is also associated with oxidative stress and a significant fall in cellular glutathione, low vitamin D, and a dramatic increase in free radical generation. Some [...]

Lowering Glutamate | Magnesium2020-05-08T11:31:25-04:00

Lowering Glutamate | Beta-caryophyllene, Copaiba, Cannabis, CBD

Beta-caryophyllene (found in Cannabis, Copaiba Essential Oil, etc) and CBD-  Protects against glutamate. “β-Caryophyllene Protects The C6 Glioma Cells Against Glutamate-Induced Excitotoxicity Through The Nrf2 Pathway.. Available from: https://www.researchgate.net/publication/265393128_b Caryophyllene_Protects_The_C6_Glioma_Cells_Against_Glutamate-Induced_Excitotoxicity_Through_The_Nrf2_Pathway [accessed Oct 26 2017].” https://www.researchgate.net/publication/265393128_b-Caryophyllene_Protects_The_C6_Glioma_Cells_Against_Glutamate-Induced_Excitotoxicity_Through_The_Nrf2_Pathway "Copaiba Oil Suppresses Inflammatory Cytokines in Splenocytes of C57Bl/6 Mice Induced with Experimental Autoimmune Encephalomyelitis" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271072/ Cannabis “Limited research carried out in humans tends to support the evidence that chronic cannabis use reduces levels of glutamate-derived metabolites in both cortical and subcortical brain areas. Research in animals tends to consistently suggest that Δ9-THC depresses glutamate synaptic transmission via CB1 receptor activation, affecting glutamate [...]

Lowering Glutamate | Beta-caryophyllene, Copaiba, Cannabis, CBD2019-09-29T07:53:19-04:00
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