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Lowering Glutamate | Andrographis

Andrographis (andrographolide)–Most commonly known as popular herb to treat Lyme, but it is also has antiviral, antibacterial, and antiparasitic properties. Most importantly, andrographis inhibits microglial activation (see below).  We have sourced ours from Sage Woman Consulting & Apothecary : Tincture & Leaf/Flower “Neuroprotective effects of andrographolide in a rat model of permanent cerebral ischaemia” “Andrographolide exhibited neuroprotective effects, with accompanying suppression of NF-κB and microglial activation, and reduction in the production of cytokines including TNF-α and IL-1β, and pro-inflammatory factors such as PGE2. Our findings suggest that andrographolide may have therapeutic value in the treatment of [...]

Lowering Glutamate | Andrographis2021-09-22T11:45:16-04:00

Lowering Glutamate | Ashwagandha

Ashwaganda (Withania somnifera)– Protects against glutamate.  Though most commonly known for aiding in adrenal fatigue, this mild herb is protective against glutamate.  We've been able to source it here and most commonly add it to our teas. Water extract from the leaves of Withania somnifera protect RA differentiated C6 and IMR-32 cells against glutamate-induced excitotoxicity. “ASH-WEX pre-treatment inhibited glutamate-induced cell death and was able to revert glutamate-induced changes in HSP70 to a large extent. Furthermore, the analysis on the neuronal plasticity marker NCAM (Neural cell adhesion molecule) and its polysialylated form, PSA-NCAM revealed that ASH-WEX has therapeutic potential for prevention [...]

Lowering Glutamate | Ashwagandha2021-09-22T11:50:42-04:00

Lowering Glutamate | Acorus Gramineus (Calamus Root aka Sweet Flag)

Acorus Gramineus (Calamus Root aka Sweet Flag) essential oil has shown to inhibit NMDA (glutamate) receptor activity, increase GABA and lower glutamate upon inhalation. We have been able to source this, here.  I will occasionally add this to our diffuser to help calm any crazy days. “These results demonstrated that EO extracted from AGR exhibited neuroprotective effects on cultured cortical neurons through the blockade of NMDA receptor activity, and that the glycine binding site appeared not to be the major site of action. ” http://www.sciencedirect.com/science/article/pii/S0024320501009444   “Furthermore, inhalation impressively inhibited the activity of gamma-aminobutyric acid (GABA) transaminase, [...]

Lowering Glutamate | Acorus Gramineus (Calamus Root aka Sweet Flag)2021-09-22T12:03:06-04:00

A Story of Hope with REID: Tics & Vocal Stimming

We occasionally get letters or comments from parents that have seen improvements in health with REID. To help provide hope to so many still in the trenches, I’ve decided to make more of an effort to share some these comments (with their permission, of course). Many of us don’t have it all figured out, but we cling to the hope and words of progress. Everyone’s journey is different, diet changes may not reap huge changes for all, but it is absolutely helping some. Like this family, glutamate and the REID diet have been a huge piece to [...]

A Story of Hope with REID: Tics & Vocal Stimming2019-09-29T17:08:45-04:00
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