Vitamin D Vitamin D is a fat-soluble vitamin that depends on a healthy gut to absorb dietary fat or fatty acid oxidation disorders (this is more common in autism, and floating stools are a sign of trouble absorbing fats). While low levels of vitamin D can induce an imbalance towards excess glutamate (excitatory neurotransmitter) and low GABA (calming neurotransmitter), vitamin D can reduce excitotoxicity (excess glutamate and excitatory neurotransmitters) through modulation of the NMDA glutamate receptor. However, in my opinion, vitamin D's most important benefit is its ability to calm microglial activation. Microglial activation occurs as [...]

Vitamin B2 aka Riboflavin Vitamin B2 (aka Riboflavin) is mainly provided by diet and bacterial synthesis in the gut. It helps to offer neuroprotection from excess glutamate, inhibits glutamate signaling (release), and helps to reduce inflammatory cytokines. Inflammatory cytokines are often the primary source of increased/excess glutamate in response to underlying immune dysfunction/activation and in response to underlying infections. All B-Vitamins help to convert food into fuel and are essential in energy production. It is important to note that vitamin-B2 (Riboflavin) is needed to break down and utilize vitamin-B6, which is important in converting excitatory glutamate [...]

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