Taurine–Beef, lamb, dark chicken meat and eggs are food sources of taurine. Why is taurine from whole food important? Commercial taurine supplements can increase sulfur which may already be high due to certain gene mutations.  Additionally, the toxins associated with yeast/candidia (which is very common) can end up depleting taurine.  Since taurine is so important in the conversion of glutmate to GABA and as an inhibitory neurotransmitter, it is important that adequate levels are achieved through diet.

“The amino acid taurine increases the GAD enzyme and consequently GABA levels. Additionally taurine doubles as an inhibitory neurotransmitter and can bind directly to GABA receptors, so it can help provide balance naturally in that manner as well. Higher levels of any inhibitory neurotransmitter help lower high levels of any excitatory neurotransmitter. Taurine is found in high levels in the brain and cardiac tissue, indicating its importance in these areas. Taurine is found most abundantly in seafood and animal protein, so it is often deficient in one’s diet. If taurine is deficient, then the GAD enzyme may be low as well, therefore, supplementing with taurine can be used to manage the GABA and glutamate balance and protect from neuron death. However, there are a couple genetic polymorphisms (particularly CBS and SUOX gene mutations) that can result in negative effects from taurine supplementation, because these mutations result in excess levels of sulfur in the body and taurine is sulfur based. If one has these gene mutations, they may also need to avoid other supplements that are high in sulfur and limit sulfur based foods. These mutations can also impair ammonia [converts to glutamate as well] detoxification as well. B6 and SAMe increases the activity of these gene mutations, so supplementation with these substances may compound the problem too.”  http://www.holistichelp.net/blog/how-to-increase-gaba-and-balance-glutamate/

Why Is This Important?

Glutamate is also the most abundant neurotransmitter, responsible for regulating over 50% of the nervous system. It is classified as an excitatory neurotransmitter, which means it excites or stimulates nerve cells located throughout the nervous system. Glutamate also has the ability to regulate other neurotransmitters, dopamine, serotonin and GABA are great examples. When glutamate is in excess it is extremely toxic to the brain and nervous system. It can become so excitatory, it is considered a excitotoxin, which means that it overstimulates brain cells to the point of killing them or damaging them enough to cause severe mitochondrial dysfunction (associated with low muscle tone) and neurological inflammation. Excess glutamate is believed to be involved in a variety of neurological and neurodegenerative disorders including autism, obsessive compulsive disorders, hyperactivity disorders, complex motor stereotypes, tics, insomnia, anxiety disorders, seizures, sensory processing disorder, addiction, depression, chronic fatigue, PANS, PANDAS, Alzheimers, and so on. Excess glutamate also impairs methylation and depletes glutathione levels, which are vital for detoxification, controlling inflammation and gut health.  Working to lower glutamate/inflammation and balance GABA, is key to improving overall health.

Obviously diet (REID) is one of the most important, if not, the most important step in lowering glutamate. However, this natural option may prove beneficial in helping when experiencing a peak of symptoms related to high glutamate and neurological inflammation, i.e. following consumption of a high glutamate food, trauma or a “flare” from PANS (pediatric autoimmune neuropsychiatric disorder) or PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections).  Additionally, working to lower inflammation/glutamate by treating underlying sources inflammation (metals, microbial imbalances, parasites, microglial activation, poor detoxification pathways, various toxins, etc.) will also be hugely beneficial.  We’ve personally found homeopathy to be great for this.

I do not have personal experience with all options mentioned in the “Lowering Glutamate” page, nor would I recommend all of them (especially the pharmaceutical options). You will want to read the comments as some of the items used to temporarily lower glutamate, can actually work to increase glutamate/glutamate sensitivity over time.

The information shared within this blog has been gathered by a mother, not a physician, and should not act as medical advice. Under no circumstances shall I, or any contributors and affiliates of the blog, be responsible for damages arising from use of the blog.